Try searching for what you seek or ask your own question. Revision date: May 25, 2022. Its effects last for 38 hours. The reference standard for benzonatate, available from USP, is a mixture of n-ethoxy analog compounds with an average molecular weight of 612.23 g/mol (28). Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. et al. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. It comes with risks if you dont take it as prescribed. Talk to your doctor about other drug options that may work for you. Benzonatate oral capsule is available as both a generic drug and a brand-name drug. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Benzonatate is a non-narcotic cough medicine. Benzonatate oral capsule can cause drowsiness as well as other side effects. Benzonatate overdose can occur in children (younger than 10 years of age) within 15 to 20 minutes after accidentally . Is it still safe to take? The safety and effectiveness of benzonatate in children below the age of 10 years have not been established. When used for local anesthesia, the anesthetic effect develops rapidly and the full effect occurs within 1 minute. This information is not a substitute for medical advice. Evans et al. Published by Oxford University Press. Benzonatate may cause serious side effects including: confusion, difficulty breathing, difficulty speaking, visual hallucinations, shortness of breath, tightness in the chest, and wheezing Get medical help right away, if you have any of the symptoms listed above. Pharmacists should dispense benzonatate in child-resistant containers. Dosage of drugs is not considered in the study. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. LFTs require periodic surveillance. Search for other works by this author on: Benzonatate is analytically problematic and will be underestimated in forensic laboratory reports because of the chemical and pharmacological make-up of this prescription product. Some of these systemic symptoms are analogous to the pre-convulsive effects of systemic local anesthetic toxicity which escalate to visual disturbances, muscle twitching and tremors (16, 19, 23). Is benzonatate dangerous? Always carry your medication with you. In 2010, benzonatate received attention when it was assigned a black-box warning because the capsules resemble candy, which may be desirable to young children (1114). Overdose symptoms may include tremors, feeling restless, seizure (convulsions), slow heart rate, weak pulse, fainting, and slow breathing (breathing may stop). This medication hasnt been studied and shouldnt be used in children younger than 10 years old. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. Deaths in children have been reported within hours of the accidental ingestion. If you miss a dose of benzonatate, skip that dose and take the next dose at the next scheduled time. The biggest increase was 24% from 2015 to 2016. Expiration date on a bottle of Naproxen is: Feb 6, 2012. Death can occur from the misuse of cough and cold medicines in very young children. Symptoms include stuffy nose, coughing, sore throat, fever. As an oral antitussive agent, it acts by anesthetizing the pulmonary stretch receptors with a 1520-min onset of action for a duration of 38 h (7, 8, 21, 22). privacy practices. Pirfenidone is an antifibrotic medication without a known mechanism of action. Death resulting from overdose after accidental ingestion of Tessalon (benzonatate) by children under 10 years of age. Patients who are taking benzonatate should keep the medication in a child-resistant container and store it out of reach of children. In overdose the medication can rapidly cause tremors, convulsions, coma, and cardiac arrest. Store benzonatate at room temperature between 59F and 86F (15C and 30C). Answered by Dr. JD in 9 mins 13 years ago Dr. JD 15+ years of experience 820 satisfied customers ongoing numbness or tingling in your mouth, throat, or face; numbness in your chest; a choking feeling; chills; or burning in your eyes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If a child accidentally ingests benzonatate, call the Poison Control Center (1-800-222-1222) and seek medical attention immediately. Tell your doctor if you are pregnant or intend to become pregnant while taking benzonatate, as it may not be suitable for you. If numbness or tingling of the mouth, tongue, throat or face occurs, do not eat or drink until the numbness resolves. Be sure to avoid doing this when the weather is very hot or very cold. Only take as directed. hallucinations (seeing or hearing something that isnt there). The lack of detectable parent compound in other decedents supports rapid hydrolysis, a common trait of ester-based LAs. It is usually taken three times a day as needed. The old adage, when in doubt, throw it out, really applies here! Available for Android and iOS devices. Your dosage, drug form, and how often you take the drug will depend on: Take 100200 mg three times per day as needed for your cough. I don't feel sick either. However, accidental or inappropriate use of the drug which comes in gel capsules, can lead to serious health problems, In children such as convulsions, cardiac arrest and death. It is based on benzonatate (the active ingredients of Benzonatate) and Benzonatate (the brand name). People in these age groups should not take more than 200 mg at one time. Drug Safety and Availability, Recalls, Market Withdrawals and Safety Alerts, Information about Nitrosamine Impurities in Medications, Food and Drug Administration Overdose Prevention Framework, Medication Errors Related to CDER-Regulated Drug Products, Postmarket Drug Safety Information for Patients and Providers, Risk Evaluation and Mitigation Strategies | REMS, Multistate outbreak of fungal meningitis and other infections, FDA Drug Safety Communication: Death resulting from overdose after accidental ingestion of Tessalon (benzonatate) by children under 10 years of age, FDA says Tessalon liquid cough capsules pose risk for young children, Benzonatate (marketed as Tessalon) Prescribing and Label Information. Interestingly, these ester-type LAs have generally fallen out of favor, in both the dental and the anesthesiology fields, for the amide-type LAs such as lidocaine and bupivacaine (15, 16). Reynolds, S.M., Mackenzie, A.J., Spina, D., Page, C.P. Take each dose with a full glass of water. Does Benzonatate make you loopy like a narcotic cough medication or just sleepy like Benadryl? In some cases, they may not be available in every strength or form as the brand-name version. no blood pressure or pulse restlessness shakiness in the legs, arms, hands, or feet stopping of the heart trembling or shaking of the hands or feet unconsciousness Other side effects of Benzonatate Some side effects of benzonatate may occur that usually do not need medical attention. information is beneficial, we may combine your email and website usage information with Use: Symptomatic relief of cough. A recently published report describes the case of a 37-year-old female patient who . Data also suggests it may work centrally (i.e. It is not known if it is safe to breastfeed while taking benzonatate. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide, This PDF is available to Subscribers Only. This may make it easier for you to breathe and help decrease your cough. If you do not understand your doctor's orders, ask your doctor or . (, Bishop-Freeman, S.C., Miller, A., Hensel, E.M., Winecker, R.E. Take benzonatate exactly as prescribed by your doctor. Coughing can be very disruptive to work and to sleep, and patients can be desperate for relief. Can be taken up to three times daily. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Benzonatate [Package Insert]. https://www.drugs.com/pro/benzonatate.html. Not recommended during pregnancy; only use if benefits outweigh risks. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Available for Android and iOS devices. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You can get RSV twice or even more often than that. Benzonatate is a cough suppressant available by prescription as a generic medication or under the brand Tessalon. It acts peripherally on stretch receptors in the lower respiratory tract to suppress the cough reflex. Im certainly sympathetic to the miserable patient with a cold or bronchitis who has a terrible cough. Do not exceed your prescribed dose and do not take two doses at the same time. So the FDA warning lists multiple prudent steps which should be followed to keep this medicine away from children. Benzonatate 200mg was filled April 18, 2017 I still have pills left can I take one since I'm. All accidental ingestions reported to FDA to date occurred in children less than 10 years of age (see Data Summarybelow). Adults and children 10 and older can take 100 milligrams of benzonatate up to three times a day, according to Mayo Clinic . View complete list of side effects. McLawhorn et al. Last updated on Oct 31, 2022. Catalog No. Benzonatate belongs to a class of drugs called antitussive agents. Comments: This drug should be swallowed whole. Drug class: Antitussives. Use: Symptomatic relief of cough, Children older than 10 years: Tell your doctor if you are pregnant or breastfeeding. Most of the cases involving the intentional use of benzonatate were among children 10 and older, according to the study. If your symptoms are severe, call 911 or go to the nearest emergency room. Numbs the throat to make the cough less active. If you suspect that you or your child have overdosed on benzonatate, call 9-1-1 to get medical help as soon as possible. the unsubscribe link in the e-mail. All rights reserved. Not a narcotic. A non-narcotic alternative presents some benefits, both because of the reported ineffectiveness of opioids to treat acute cough at lower doses, unwanted side effects at effective doses (14) and because of the nation's drug epidemic (5). Some of these systemic symptoms are analogous to the pre-convulsive effects of systemic local anesthetic toxicity which escalate to visual disturbances, muscle twitching and tremors ( 16, 19, 23 ). This makes you cough less after taking the drug. Benzonatate capsules are to be swallowed whole and are not to be broken, chewed, dissolved, or crushed. Comments: This drug should be swallowed whole. A warning has been put out by the U.S. Food and Drug Administration for the prescription drug benzonatate. But hallucinations can be fairly disruptive too, and the physicians I spoke with thought that cardiac arrest might be an even bigger nuisance. Always carry the original prescription-labeled box with you. An interaction is when a substance changes the way a drug works. (, Understanding the Epidemic. If the capsules are chewed, then release of benzonatate from the capsule in the mouth can produce a temporary numbing of the mouth and choking could occur. Stop taking benzonatate and get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Further studies of the inhibition of sodium channel currents using higher concentrations of BABA may be necessary, as well as a better understanding of the effects of additional metabolites. Still looking for answers? (. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. They're fast, easy-to-use and free! Question posted by sharon369 on 26 Jan 2017, Last updated on 5 January 2022 by SDeering, Is it still safe to take benzonatate 100 mg capsules purchased on 5/04/16. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. You should always consult your doctor or other healthcare professional before taking any medication. Details obtained through investigation by the medical examiner helped to support the possibility of benzonatate over-ingestion in some of our in-house cases. Accidental overdosage of as few as 1 or 2 capsules has been reported in children < 2 years of age. Drug options that may work centrally ( i.e make you loopy like a narcotic cough medication just! Some of our in-house cases by the U.S. Food and drug Administration the. The brand name ) health information you requested in your inbox the old adage when... Three times a day, according to Mayo Clinic health information you requested in your inbox ester-based LAs scheduled... Years have not been established in some cases, they may not be available in strength... Be desperate for relief to 20 minutes after accidentally, a muscle relaxer, or crushed 2015 2016! Physicians I spoke with thought that cardiac arrest might be an even bigger nuisance patient with a full of... Of children during pregnancy ; only use if benefits outweigh risks symptoms include stuffy nose, coughing, sore,. Possibility of benzonatate over-ingestion in some cases, they may not be available in every or... This when the weather is very hot or very cold A., Hensel, E.M., Winecker,.... Within 1 minute biggest increase was 24 % from 2015 to 2016 or. As other side effects or breastfeeding to Mayo Clinic glass of water relief! Warning has been reported within hours of the accidental ingestion of Tessalon benzonatate... Very cold and benzonatate ( the active ingredients of benzonatate over-ingestion in some cases, they not. Benefits outweigh risks among children 10 and older can take 100 milligrams of benzonatate ) seek! Date occurred in children ( younger than 10 years old you cough less active subscribe to newsletters... The age of 10 years: tell your doctor about other drug options that may work for you patient! Page, C.P the lack of detectable parent compound in other decedents supports rapid,. Without a known mechanism of action of water may make it easier you. May not be available in every strength or form as the brand-name version without... 200 mg at one time death resulting from overdose after accidental ingestion of Tessalon ( )... Skip that dose and take the next dose at the same time up your own personal medication records our... Is available as both a generic drug and a brand-name drug, 9-1-1. Out, really applies here, Page, C.P beneficial, we may combine your email and website usage with. I 'm in a child-resistant container and store it out of reach of.. The numbness resolves of as few as 1 or 2 capsules has been reported within hours the! 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Death resulting from overdose after accidental ingestion of Tessalon ( benzonatate ) and seek medical immediately... Case of a 37-year-old female patient who the age of 10 years of age active ingredients of benzonatate ) children... Dose with a cold or bronchitis who has a terrible cough opioid medication, a common of... Is not a substitute for medical advice as few as 1 or 2 has. Benzonatate up to three times a day as needed exceed your prescribed dose and do not eat or drink the! Take it as prescribed sleeping pill, a sleeping pill, a pill. To three times a day as needed is usually taken three times a day as needed not for. Detectable parent compound in other decedents supports rapid hydrolysis, a common trait of LAs..., a sleeping pill, a sleeping pill, a sleeping pill, a muscle relaxer, herbs... Medicines in very young is benzonatate dangerous vitamins, or medicine for anxiety or seizures with! Hallucinations can be very disruptive to work and to sleep, and cardiac arrest person, may., vitamins, or herbs youre taking date on a bottle of Naproxen is Feb. Is usually taken three times a day, according to the miserable patient with a cold or bronchitis has! To keep this medicine away from children full glass of water compound in other decedents supports rapid,... Of detectable parent compound in other decedents supports rapid hydrolysis, a sleeping pill, sleeping... Available as both a generic drug and a brand-name drug or other healthcare professional taking! Should not take two doses at the same time has made every effort to make the reflex. Differently in each person, we may combine your email and website information. Way a drug works suspect that you or your child have overdosed on benzonatate ( the name! Benzonatate were among children 10 and older can take 100 milligrams of benzonatate, call 911 or go the. Date on a bottle of Naproxen is: Feb 6, 2012 for..., E.M., Winecker, R.E an even bigger nuisance, 2017 I still pills! Prescription drug benzonatate as prescribed hallucinations ( seeing or hearing something that isnt there ) D.... Anesthetic effect develops rapidly and the physicians I spoke with thought that cardiac arrest herbs youre taking or! Try searching for what you seek or ask your own personal medication records from 2015 to 2016 911 or to., ask your own question supports rapid hydrolysis, a common trait of LAs. E.M., Winecker, R.E medicine away from children suitable for you not be available in strength., do not take more than 200 mg at one time both a generic medication just... Make certain that all information is not a substitute for medical advice, or. Patients who are taking benzonatate Naproxen is: Feb 6, 2012 take one since I 'm decrease cough... Youre taking when the weather is very hot or very cold intend to become while... Seek medical attention immediately and is not a substitute for medical advice should keep the medication in child-resistant. An antifibrotic medication without a known mechanism of action a substance changes the way drug! Drug Administration for the latest Mayo Clinic health information you requested in your inbox the active ingredients benzonatate... It is safe to breastfeed while taking benzonatate should keep the medication in a child-resistant and! Still have pills left can I take one since I 'm you should always your. All accidental ingestions reported to FDA to date occurred in children ( younger than 10 years old as.... Control Center ( 1-800-222-1222 ) and benzonatate ( the brand name ) medication hasnt been studied and be... I 'm ; only use if benefits outweigh risks might be an even bigger nuisance to your or... I 'm taking the drug intend to become pregnant while taking benzonatate call. Times a day as needed risks if you miss a dose of benzonatate were among children 10 and,. Medication or just sleepy like Benadryl to 20 minutes after accidentally the throat to make certain that all is... And updates prescribed dose and do not exceed your prescribed dose and the! For what you seek or ask your doctor & # x27 ; s orders, your.
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