GrandeLash-MD Isopropyl cloprostenate is a synthetic prostaglandin analog that works by lowering the intraocular pressure in glaucoma patients. The prostaglandins often stimulate the melanocytes to produce more melanin, changing the color of the eye. However, neulash was quick to change its formulation and now it is better than ever. Eye redness: Iris color change; ... “Isopropyl cloprostenate is an active ingredient commonly found in medications used to treat glaucoma. Isopropyl cloprostenate has never been approved by the FDA as a drug. I do not know about this product. An FDA-warning letter mentions among others ocular irritation, hyperemia, iris color change… RapidLash has been reformulated, but … Side effects may include irritation, iris color change, inflammation and eye pressure changes. Glaucoma is a disease involving high intraocular pressure, and isopropyl cloprostenate works to lower the intraocular pressure. If the patient will use the drug in both eyes, you should still have the discussion, even though asymmetry won’t be an issue. According to the complaint, alleged side effects included “change(s) in iris color, eyelid drooping, itchy eyes, eye/lid discoloration, eye sensitivity and vision impairment.” In response to the lawsuit, R+F said in a statement that it had always marketed Lash Boost as a cosmetic and had been transparent about side effects all along. One only has to check out the ingredients on the box of the fancy lash serum to find isopropyl cloprostenate still listed. In 2012 this product was recalled in Sweden for the reason that isopropyl cloprostenate, which was an ingredient at the time, was found to cause redness, itching and even change of eye color by the FDA. Not all chemicals are created alike. Isopropyl Cloprostenate (ICP) is a cosmetic ingredient, not a medical grade ingredient such as found in prescription lash products with their associated side effects. A number of different adverse side effects have been associated with isopropyl cloprostenate including macular edema, dry eye, eye redness, eye inflammation, eye irritation, color change of the iris, and low intraocular pressure. Learn More. Latisse can change the color of your iris (the colored part of your eye). I believe it is relative to the prostaglandins in Latisse. All of their literature warns about this, and the doctor reiterated this might happen. After reading your articles on lash growth serum my conclusion is none of them are free from side effects. Patients should be aware of this possibility, just as they should know that the drug might change their eye color—an effect that some patients don’t mind, but others do. ... iris color change, inflammation, and eye pressure changes. ISOPROPYL CLOPROSTENATE Synthetic prostaglandin analogue found in several lash and brow enhancing formulas. All R + F products are sold with a 60 day moneyback guarantee. I recently bought Dr. Lara Devgan Platinum Lash Serum as it lists no eye color change - but I see it is false advertisement as one of the ingredients listed is Myristoyl Pentapeptide-17. Not approved by FDA. Isopropyl cloprostenate is a synthetic type of compound known as a prostaglandin analog, which is required to be labeled as a drug by the FDA. To provide more explanation, we can clarify the chemical category in question - prostaglandins. The chemical can produce side effects such as ocular irritation, hyperemia, iris color change, macular edema and ocular inflammation when not supervised by a licensed practitioner. 9. The doctor reiterated this might happen in several lash and brow enhancing formulas (! Their literature warns about this, and eye pressure changes latisse can change color! 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